Autoimmunity is the system of immune responses of an organism against its own healthy cells, tissues and other body normal constituents. Many autoimmune diseases are caused by such autoantibodies. The study was carried out to critically examine Autoimmunity and Inflammation in the human body system. When the body encounters something foreign in its environment it needs to be able to mount an immune response against that substance to protect itself from potential harm. In order to do this effectively it must be able to recognize what is self in order to respond to non-self or foreign. In autoimmune disease there is a failure to recognize some part of self, with potential serious consequence Autoimmune disease disorders and its usually accompanying symptom, inflammation result in destruction of one or more types of body tissues abnormal growth of an organ, or changes in organ function. The disorder may affect only one organ or tissue type or many affect multiple organ and tissue. Organs and tissues, commonly affected include blood components such as red blood cells, blood vessels, connective tissue, endocrine glands such as the thyroid or pancreas, muscles, joints and skin.
1.1 Introduction
In this section, a Critical Examination of Autoimmunity and Inflammation is discussed, with relevant and recent citations. As a prelude to other parts of this study, this chapter will discuss the background upon which this study was initiated, the statement of problems that led to this study, the aim and objectives of the study. Others are significance of the study, scope of work, research hypothesis and questions, limitation of the study and definition of terms.