Kaka bitters like other bitters is claimed to possess a number of folkloric therapeutic effects including lipid-lowering effects. However, there is no scientific data available as at the time of this study to evidence this claim. The Lipid-lowering effects of Kaka bitters were investigated by assessing it effects on the blood lipid parameters of wistar rats fed fat-enhanced diet. The was divided into three (3) groups: Group 1 rats was fed normal feed with distilled water; Group 2 was fed fat-enhanced diet with distilled water and Group 3 was fed fat-enhanced diet with Kaka bitters. The result obtained shows that blood TG levels decreased in group 3 rats compared with group 2, but the decrease is not statistically significant (p Also there was a statistically significant decrease in blood HDL levels and also statistically significant increase in total cholesterol and LDL levels of group 3 rats compared with group 2 (p
1.1 Introduction
In this section, the Effect of Kaka Bitters on Lipid profile of Wistar Rats Fed with High Fat Diet is discussed, with relevant and recent citations. As a prelude to other parts of this study, this chapter will discuss the background upon which this study was initiated, the statement of problems that led to this study, the aim and objectives of the study. Others are significance of the study, scope of work, research hypothesis and questions, limitation of the study and definition of terms.