The study investigates the in vitro antimicrobial activity of Indian medicinal plants Calotrophs procera and Calotrophs Asatica linn against the resistant pathogens. In achieving this aim, the following specific objectives were laid out to identify the economic importance of Calotropis procera Bombom, assess the nutritional importance of Calotropis procera Bombom, and investigate in vitro anti microbial activity of aerial parts of Calotropis procera and Centella asatica Linn., that have been popularly used as folk medicines. The organic solvent plant extracts are tested on the various micro-organisms including bacteria and fungi using agar well diffusion technique. The length of the inhibition zone was measured in millimeters from the edge of the well to the edge of the inhibition zone. Calotropis procera showed significant to moderate activity against (14mm) Pseudomonas marginalis and (21mm) Streptococcus mutans with 100mg/ml DMSO plant drug concentration. The results of (MICs) values are lowest at 66 and highest at 152mg/ml for Calotropis asatica. The extracts were assessed in an effort to validate the potential activity of the medicinal plant plants against microbes.
1.1 Introduction
In this section, Nutritional and Economic Importance of Giant Milk Weed is discussed, with relevant and recent citations. As a prelude to other parts of this study, this chapter will discuss the background upon which this study was initiated, the statement of problems that led to this study, the aim and objectives of the study. Others are significance of the study, scope of work, research hypothesis and questions, limitation of the study and definition of terms.