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A Critical Examination of Autoimmunity and Inflammation

A Critical Examination of Autoimmunity and Inflammation

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DEDICATION

This research material, titled “A Critical Examination of Autoimmunity and Inflammation” is dedicated to God for His boundless grace and guidance. It is also a tribute to all computer enthusiasts whose contributions made my research journey smoother and enriched my documentation process, making the experience truly fulfilling.




ACKNOWLEDGEMENT

I am profoundly grateful to everyone who contributed to the successful completion of this project. I am especially grateful to my Supervisor (Name), the Head of Department (Name), and the Lecturers in the Department of Biochemistry for their invaluable guidance and support. I also acknowledge the contributions of authors and scholars whose works on A Critical Examination of Autoimmunity and Inflammation provided essential insights. Special thanks go to my study area (and any funding organizations, if applicable) for their financial assistance. I am equally thankful to stakeholders, including mentors, teachers, and colleagues, for their encouragement and support. Finally, I deeply appreciate my family and friends for their patience and unwavering support throughout this journey. Your contributions have been instrumental in making this research a reality.




PRELIMINARY PAGES


CHAPTER ONE

INTRODUCTION

  • 1.1 Introduction
  • 1.2 Background of Study
  • 1.3 Statement of Problems
  • 1.4 Aim and Objectives of Study
  • 1.5 Research Questions
  • 1.6 Research Hypothesis
  • 1.7 Significance of Study
  • 1.8 Scope of Study
  • 1.9 Limitations of the Study
  • 1.10 Definition of Terms

CHAPTER TWO

LITERATURE REVIEW

  • 2.1 Introduction
  • 2.2 Conceptual Review of Autoimmunity
  • 2.3 Types of Auto Immunity
  • 2.4 Overview of Inflammation
  • 2.4.1 Health Benefits of Inflammation
  • 2.4.2 Types of Inflammation
  • 2.4.3 Remedies of Inflammation
  • 2.4.4 Causes and Effect of Inflammation
  • 2.4.5 Possible Treatments for Inflammation
  • 2.5 Overview of Autoimmune Diseases
  • 2.5.1 Common Autoimmune Disease Symptoms
  • 2.5.2 Autoimmune Disease Risk Factors
  • 2.6 Theoretical Framework
  • 2.6.1 Pathogenesis of Autoimmunity
  • 2.6.1.1 Genetic Factors of Pathogenesis
  • 2.6.1.2 Environmental Factors
  • 2.6.1.3 Other Factors
  • 2.6.2 Evidence for Pathogenicity of Autoantibodies to Intracellular Antigens
  • 2.7 People at Risk for Autoimmune Disease
  • 2.8 Diagnosis of Autoimmune Disorders
  • 2.9 Treatment of Autoimmunity

CHAPTER THREE

RESEARCH METHODOLOGY

  • 3.1 Introduction
  • 3.2 Research Design
  • 3.3 Population of Study
  • 3.4 Sampling and Sampling Technique
  • 3.5 Validation of Research Instrument
  • 3.6 Method of Data Collection
  • 3.7 Method of Data Analysis
  • 3.8 Questionnaire
  • 3.8.1 Interview
  • 3.8.2 Key Informants Interview
  • 3.8.3 Observation
  • 3.9 Statistical Analysis

CHAPTER FOUR

DATA ANALYSIS, RESULT AND DISCUSSION

  • 4.1 Introduction
  • 4.2 Presentation and Analysis of Data
  • 4.3 Test of Hypothesis 1
  • 4.4 Discussion of Findings

CHAPTER FIVE

SUMMARY, CONCLUSION AND RECOMMENDATION

  • 5.1 Introduction
  • 5.2 Summary
  • 5.3 Conclusion
  • 5.4 Recommendation

REFERENCES

APPENDIX A - “QUESTIONNAIRE”



ABSTRACT

Autoimmunity is the system of immune responses of an organism against its own healthy cells, tissues and other body normal constituents. Many autoimmune diseases are caused by such autoantibodies. The study was carried out to critically examine Autoimmunity and Inflammation in the human body system. When the body encounters something foreign in its environment it needs to be able to mount an immune response against that substance to protect itself from potential harm. In order to do this effectively it must be able to recognize what is self in order to respond to non-self or foreign. In autoimmune disease there is a failure to recognize some part of self, with potential serious consequence Autoimmune disease disorders and its usually accompanying symptom, inflammation result in destruction of one or more types of body tissues abnormal growth of an organ, or changes in organ function. The disorder may affect only one organ or tissue type or many affect multiple organ and tissue. Organs and tissues, commonly affected include blood components such as red blood cells, blood vessels, connective tissue, endocrine glands such as the thyroid or pancreas, muscles, joints and skin.



A Critical Examination of Autoimmunity and Inflammation


1.1 Introduction

… As a prelude to other parts of this study, this chapter will discuss the background upon which this study was initiated, the statement of problems that led to this study, the Aim and Objectives of the study. Others are Significance of the study, Scope of work, Research hypothesis and questions, Limitation of the study and Definition of technical terms.…


CHAPTER TWO

2.0 Literature Review

2.1 Introduction

This chapter focuses on the review of related literature. A literature review includes the current knowledge as well as theoretical and methodological contributions to a particular topic. It documents the state of the art with respect to the topic you are writing. It surveys the literature in the topic selected. In this research work the literature review includes the conceputal review, theoretical framework, the review of related literature …

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Defense Procedure for Biochemistry Researchers


In preparation for defending a project or seminar on A Critical Examination of Autoimmunity and Inflammation, it is imperative that as a nursing student, you demonstrate comprehensive knowledge of your research. The defense process is structured to include presenting your work, answering questions, and illustrating its pertinence. Initially, provide a succinct yet thorough introduction to your research topic, emphasizing its importance and the objectives, ensuring that both the audience and the External Examiner can understand the scope of your study.


Prior to your defense, be thoroughly acquainted with your research abstract and the critical elements of Chapter One, including motivation for embarking on this research, problem statement, objectives, and significance. In Chapter Two, be ready to cite at least two references from the literature review. For Chapter Three, you should be equipped to discuss the methodologies, tools, and techniques utilized. In Chapter Four, defend your research by justifying the findings and linking them to your research objectives.


Conclude your defense by succinctly summarizing the study and offering insightful, evidence-based recommendations. A professional dress code, such as wearing a suit and tie, is vital to create a favorable impression and elevate your presentation.


During the question and answer segment, the External Examiner may pose questions pertaining to your research. If confronted with a challenging or irrelevant question, respond diplomatically with, “Sorry, Sir/Madam, the question asked is beyond the scope of my study.” Whenever possible, direct your answers back to your research findings to reinforce your expertise.


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