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A Critical Examination of Autoimmunity and Inflammation

A Critical Examination of Autoimmunity and Inflammation

Project / Seminar Material
Reference ID: PS-2969-TM

DEDICATION

This research material titled “A Critical Examination of Autoimmunity and Inflammation” is dedicated to God for his enabling grace, and to all computer enthusiasts who contributed to make life a pleasant experience during my research documentation.

ACKNOWLEDGEMENT

I extend my sincere gratitude to all those who contributed to the completion of this project. Special thanks to my Supervisor (Name of your Supervisor), the Head of Department (Name of your HOD), the Lecturers in the department of Biochemistry, Book Authors and Profound Scholars of existing or related project material on “A Critical Examination of Autoimmunity and Inflammation” for their invaluable guidance, support, and expertise throughout the journey.

I am also grateful to your study area (mention any funding organizations, if applicable) for their financial assistance. This research would not have been possible without the encouragement and assistance of some stakeholders (mention any mentors, teachers, or colleagues). Additionally, I would like to acknowledge the understanding and patience of my family and friends during this endeavor. Your unwavering support has been a constant source of motivation. Thank you all for being part of this meaningful endeavor.


A Critical Examination of Autoimmunity and Inflammation

TABLE OF CONTENTS

PRELIMINARY PAGES


CHAPTER ONE

INTRODUCTION

  • 1.1 Introduction
  • 1.2 Background of Study
  • 1.3 Statement of Problems
  • 1.4 Aim and Objectives of Study
  • 1.5 Research Questions
  • 1.6 Research Hypothesis
  • 1.7 Significance of Study
  • 1.8 Scope of Study
  • 1.9 Limitations of the Study
  • 1.10 Definition of Terms

CHAPTER TWO

LITERATURE REVIEW

  • 2.1 Introduction
  • 2.2 Conceptual Review of Autoimmunity
  • 2.3 Types of Auto Immunity
  • 2.4 Overview of Inflammation
  • 2.4.1 Health Benefits of Inflammation
  • 2.4.2 Types of Inflammation
  • 2.4.3 Remedies of Inflammation
  • 2.4.4 Causes and Effect of Inflammation
  • 2.4.5 Possible Treatments for Inflammation
  • 2.5 Overview of Autoimmune Diseases
  • 2.5.1 Common Autoimmune Disease Symptoms
  • 2.5.2 Autoimmune Disease Risk Factors
  • 2.6 Theoretical Framework
  • 2.6.1 Pathogenesis of Autoimmunity
  • 2.6.1.1 Genetic Factors of Pathogenesis
  • 2.6.1.2 Environmental Factors
  • 2.6.1.3 Other Factors
  • 2.6.2 Evidence for Pathogenicity of Autoantibodies to Intracellular Antigens
  • 2.7 People at Risk for Autoimmune Disease
  • 2.8 Diagnosis of Autoimmune Disorders
  • 2.9 Treatment of Autoimmunity

CHAPTER THREE

RESEARCH METHODOLOGY

  • 3.1 Introduction
  • 3.2 Research Design
  • 3.3 Population of Study
  • 3.4 Sampling and Sampling Technique
  • 3.5 Validation of Research Instrument
  • 3.6 Method of Data Collection
  • 3.7 Method of Data Analysis
  • 3.8 Questionnaire
  • 3.8.1 Interview
  • 3.8.2 Key Informants Interview
  • 3.8.3 Observation
  • 3.9 Statistical Analysis

CHAPTER FOUR

DATA ANALYSIS, RESULT AND DISCUSSION

  • 4.1 Introduction
  • 4.2 Presentation and Analysis of Data
  • 4.3 Test of Hypothesis 1
  • 4.4 Discussion of Findings

CHAPTER FIVE

SUMMARY, CONCLUSION AND RECOMMENDATION

  • 5.1 Introduction
  • 5.2 Summary
  • 5.3 Conclusion
  • 5.4 Recommendation

REFERENCES

APPENDIX A - “QUESTIONNAIRE”

ABSTRACT

Autoimmunity is the system of immune responses of an organism against its own healthy cells, tissues and other body normal constituents. Many autoimmune diseases are caused by such autoantibodies. The study was carried out to critically examine Autoimmunity and Inflammation in the human body system. When the body encounters something foreign in its environment it needs to be able to mount an immune response against that substance to protect itself from potential harm. In order to do this effectively it must be able to recognize what is self in order to respond to non-self or foreign. In autoimmune disease there is a failure to recognize some part of self, with potential serious consequence Autoimmune disease disorders and its usually accompanying symptom, inflammation result in destruction of one or more types of body tissues abnormal growth of an organ, or changes in organ function. The disorder may affect only one organ or tissue type or many affect multiple organ and tissue. Organs and tissues, commonly affected include blood components such as red blood cells, blood vessels, connective tissue, endocrine glands such as the thyroid or pancreas, muscles, joints and skin.


A Critical Examination of Autoimmunity and Inflammation

CHAPTER ONE

1.1 Introduction

… As a prelude to other parts of this study, this chapter will discuss the background upon which this study was initiated, the statement of problems that led to this study, the Aim and Objectives of the study. Others are Significance of the study, Scope of work, Research hypothesis and questions, Limitation of the study and Definition of technical terms.

CHAPTER TWO

2.0 Literature Review

2.1 Introduction

This chapter focuses on the review of related literature. A literature review includes the current knowledge as well as theoretical and methodological contributions to a particular topic. It documents the state of the art with respect to the topic you are writing. It surveys the literature in the topic selected. In this research work the literature review includes the …

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