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Effects of Vitamin Supplementation on Lead Toxicity in Wistar Albino Rats

Effects of Vitamin Supplementation on Lead Toxicity in Wistar Albino Rats

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DEDICATION

This research material, titled “Effects of Vitamin Supplementation on Lead Toxicity in Wistar Albino Rats” is dedicated to God for His boundless grace and guidance. It is also a tribute to all computer enthusiasts whose contributions made my research journey smoother and enriched my documentation process, making the experience truly fulfilling.



ACKNOWLEDGEMENT

I am profoundly grateful to everyone who contributed to the successful completion of this project. I am especially grateful to my Supervisor (Name), the Head of Department (Name), and the Lecturers in the Department of Biochemistry for their invaluable guidance and support. I also acknowledge the contributions of authors and scholars whose works on Effects of Vitamin Supplementation on Lead Toxicity in Wistar Albino Rats provided essential insights. Special thanks go to my study area (and any funding organizations, if applicable) for their financial assistance. I am equally thankful to stakeholders, including mentors, teachers, and colleagues, for their encouragement and support. Finally, I deeply appreciate my family and friends for their patience and unwavering support throughout this journey. Your contributions have been instrumental in making this research a reality.



TABLE OF CONTENTS

PRELIMINARY PAGES

CHAPTER ONE

INTRODUCTION

    CHAPTER TWO

    LITERATURE REVIEW

    • 2.1 Introduction
    • ⋮

    CHAPTER THREE

    MATERIALS AND METHODS

    • 3.1 Introduction
    • ⋮

    CHAPTER FOUR

    RESULTS AND DISCUSSION

    • 4.1 Introduction
    • 4.2 Results
    • ⋮
    • 4.3 Discussion of Findings

    CHAPTER FIVE

    SUMMARY, CONCLUSION AND RECOMMENDATION

    • 5.1 Introduction
    • 5.2 Summary
    • 5.3 Conclusion
    • 5.4 Recommendation

    REFERENCES


    ABSTRACT

    Oxidative stress is one of the mechanisms involved in lead poisoning. Air Max 2016 Heren Goedkoop Goedkope Nike Air Max schonenen The present study investigated the role of ascorbic acid, thiamine, pyridoxine, tocopherol, individually and in cocktail in mitigating the biochemical alterations induced by subchronic administration of 500mg/kg of lead acetate for 6 weeks. Air Max 2015 Zwwart Rood Goedkoop Thirty — five wistar albino rats divided into seven groups of five animals in each group were used for this study. Nike Free 5.0 V4 Goedkoop nike air max 1 pas cher. All the animals were fed ad libitum. The first group which served as the negative control received no treatment. Nike REE 3.0 V4 Goedkoop asics tiger pas cher.

    The second group which served as the positive control had 500mg of lead acetate added per kg of feed. Nike Air Max Thea Print Dame authentique. All other groups received same regimen as the second group but in addition, four other groups received 300mg/kg diet of pyridoxine, thiamine, ascorbic acid and tocopherol respectively, while the last group received 300mg of vitamin mixture containing 75mg each of thiamine, pyridoxine, ascorbic acid and tocopherol per kg of diet. Lunettes de soleil Ray Ban, The rats were sacrificed after 6 weeks and sera obtained from the blood samples were analysed for alanine transaminase(ALT), aspartate transaminase (AST) and alkaline phosphatase (ALP) activities. Nike FS Lite Run Goedkoop Urea and creatinine concentrations were also evaluated.

    The results indicated that exposure of the animals to lead resulted in a significant increase (pThe activities of ALT, AST and ALP as well as the levels of urea and creatinine were significantly lower (p


    Effects of Vitamin Supplementation on Lead Toxicity in Wistar Albino Rats

    CHAPTER ONE

    1.1 Introduction

    … As a prelude to other parts of this study, this chapter will discuss the background upon which this study was initiated, the statement of problems that led to this study, the Aim and Objectives of the study. Others are Significance of the study, Scope of work, Research hypothesis and questions, Limitation of the study and Definition of technical terms.…

    CHAPTER TWO

    2.0 Literature Review

    2.1 Introduction

    This chapter focuses on the review of related literature. A literature review includes the current knowledge as well as theoretical and methodological contributions to a particular topic. It documents the state of the art with respect to the topic you are writing. It surveys the literature in the topic selected. In this research work the literature review includes the conceputal review, theoretical framework, the review of related literature …

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    Defense Procedure for Biochemistry Researchers

    In preparation for defending a project or seminar on Effects of Vitamin Supplementation on Lead Toxicity in Wistar Albino Rats, it is imperative that as a nursing student, you demonstrate comprehensive knowledge of your research. The defense process is structured to include presenting your work, answering questions, and illustrating its pertinence. Initially, provide a succinct yet thorough introduction to your research topic, emphasizing its importance and the objectives, ensuring that both the audience and the External Examiner can understand the scope of your study.

    Prior to your defense, be thoroughly acquainted with your research abstract and the critical elements of Chapter One, including motivation for embarking on this research, problem statement, objectives, and significance. In Chapter Two, be ready to cite at least two references from the literature review. For Chapter Three, you should be equipped to discuss the methodologies, tools, and techniques utilized. In Chapter Four, defend your research by justifying the findings and linking them to your research objectives.

    Conclude your defense by succinctly summarizing the study and offering insightful, evidence-based recommendations. A professional dress code, such as wearing a suit and tie, is vital to create a favorable impression and elevate your presentation.

    During the question and answer segment, the External Examiner may pose questions pertaining to your research. If confronted with a challenging or irrelevant question, respond diplomatically with, “Sorry, Sir/Madam, the question asked is beyond the scope of my study.” Whenever possible, direct your answers back to your research findings to reinforce your expertise.

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