Cervical screening is the process of detecting and removing abnormal tissue or cells in the cervix before cervical cancer develops. The aim of the study is to examine the Knowledge and Perception of Cervical Cancer Screening among University of Benin Female Students. In achieving this aim, the following specific objectives were laid out as follows to: determine the knowledge and acceptability of Cervical Cancer Screening, assess the knowledge, attitude and practice towards cervical cancer and screening among University of Benin Female Students, carry out health education on cervical cancer and screening, which is the intervention group, and assess the effect of health education on knowledge, attitude and uptake of cervical cancer screening among Female Students in University of Benin. The research design used in this report is descriptive design, utilizing questionnaire method to obtain information from the respondents for this project. Primary data were collected from the primary source which questionnaire was used as an instrument of data collection while secondary data were sources from textbooks, journals, newspapers and the internet were employed. The data were presented on a frequency distribution table and analyzed using simple percentage, while hypothesis was tested using chi-square test. The study will be beneficial to teachers which are stakeholders in health and are means through which the twin goal of health for all and education for all can be achieved. Therefore reducing morbidity and mortality among them through cervical cancer prevention is paramount to the achievement of millennium development goals. Based on the findings, it is recommended that creating awareness for cervical cancer through mass media campaign on television, radio, national newspaper, local or community newspaper by the relevant department of the Ministry of Health