This page presents an excerpt of the research material, providing a comprehensive overview of the study. It includes the Preliminary Pages, Table of Contents, Abstract, Chapters One to Five, and References, making it accessible and informative for students, researchers, and other readers interested in the topic of this study. Acknowledgement is also included, expressing gratitude to the individuals, institutions, and resources that contributed to the successful completion of the research, with materials and information sourced from the online platform sparklyn.com.ng, which provided valuable academic support.
PRELIMINARY PAGES
- Title page
- Approval page
- Dedication
- Acknowledgement
- Table of Contents
- Abstract
CHAPTER ONE
INTRODUCTION
CHAPTER TWO
LITERATURE REVIEW
CHAPTER THREE
MATERIALS AND METHODS
CHAPTER FOUR
RESULTS AND DISCUSSION
- 4.1 Introduction
- 4.2 Results
- ⋮
- 4.3 Discussion of Findings
CHAPTER FIVE
SUMMARY, CONCLUSION AND RECOMMENDATION
- 5.1 Introduction
- 5.2 Summary
- 5.3 Conclusion
- 5.4 Recommendation
REFERENCES
The effect of leaf extract of ocimum gratissimium (scent leaf) and vernonia Amygdalina (bitter leaf) under nicotinanmide coverage was studied using albino wistar rat. Acute toxicity of the plant was carried out using (Lorkes method). LD50 was calculated to be 208 mglkg. The main work involved 49 albino wistar rats weighing 150g to 200g. The rats were put in 7 groups of 7 rats each. Rats in group I served as the control and were administered distilled water and feed. Rats in Groups II-VII were administered OG, V.A, DM+NICO, DM+NICO+OG, DM+NICO+VA, DM+NICO+OG+VA respectively for 28 days according to their body weight. Oral administration was used for all the groups. The result obtained showed the mean± SEM P values (P<0.05) was taken as significant. DM + NICO + OG lowered (P<0.05) the VLDL level. DM + NICO + VA lowered (P<0.05) T − CHOL level compared to the control but DM + NICO + VA was seen to raise T-CHOL level. DM + NICO + OG +V.A significantly lowered (P<0.05) the TG level compared to control, O.G and DM + NICO + VA + O.G groups. According to the study, NICO + V.A lowers Lipid profile. O.G increases LDL levels thereby increasing the risk of atherosclerosis and cardiovascular complication.
1.1 Introduction
In this section, Study of Lipid Profile in Streptozotocin (Stz) - Induced Diabetic Rats Under Nicotinamide Coverage Treated with Ocimum Gratissimum (O.G.) and Vernonia Amygdalina (V.A.) is discussed, with relevant and recent citations. As a prelude to other parts of this study, this chapter will discuss the background upon which this study was initiated, the statement of problems that led to this study, the aim and objectives of the study. Others are significance of the study, scope of work, research hypothesis and questions, limitation of the study and definition of terms.
This chapter focuses on the review of related literature. A literature review presents current knowledge, as well as theoretical and methodological contributions, related to Study of Lipid Profile in Streptozotocin (Stz) - Induced Diabetic Rats Under Nicotinamide Coverage Treated with Ocimum Gratissimum (O.G.) and Vernonia Amygdalina (V.A.). It documents the state of the art on the subject under study and provides a comprehensive survey of existing literature. In this research work the literature review includes the conceputal review, theoretical framework, the review of related literature …
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