Project Topics Seminar Topics School of Nursing Exam PDF Sign Up
Search Topic
PARKLYN
ERVICES
 · RC: 2994849
The Effects of Methanol Extract of Dennettia Tripetala (Mmimi) on the Liver Marker Enzymes (AST, ALT and ALP) of Albino Rats
WhatsApp Channel

The Effects of Methanol Extract of Dennettia Tripetala (Mmimi) on the Liver Marker Enzymes (AST, ALT and ALP) of Albino Rats

This page presents an excerpt of the available research material, including the Preliminary Pages, Table of Contents, Abstract, Chapters One to Five, and References. It provides a comprehensive overview of the study, enhancing readability and accessibility for students, and researchers seeking complete material on the topic stated above.

ACKNOWLEDGEMENT

I am profoundly grateful to everyone who contributed to the successful completion of this project. I am especially grateful to my Supervisor (Name), the Head of Department (Name), and the Lecturers in the Department of Science Laboratory Technology (SLT) for their invaluable guidance and support. I also acknowledge the contributions of authors and scholars whose works on The Effects of Methanol Extract of Dennettia Tripetala (Mmimi) on the Liver Marker Enzymes (AST, ALT and ALP) of Albino Rats provided essential insights. Special thanks go to my study area (and any funding organizations, if applicable) for their financial assistance. I am equally thankful to stakeholders, including mentors, teachers, and colleagues, for their encouragement and support. Finally, I deeply appreciate my family and friends for their patience and unwavering support throughout this journey. Your contributions have been instrumental in making this research a reality.



ABSTRACT

The effect of oral administration of methanol extract of Dennettia tripetala on the activity of liver marker enzymes: Alkaline phosphatase (ALP), Aspartate Aminotransferase (AST) and Alanine Aminotransferase(ALT) in the serum of albino rats was investigated. A total of Nine (9) albino rats(Rattus norvegicus spp)weighing between 150-200g were used for the study and randomly assigned into three study groups of three animals each. The group 3 (control) received via oral route a placebo (4ml of normal saline) while test group 1 and 2 received 85mg/kg body weight and 170mg/kg weight of Dennettia tripetala extract in 2.0ml and 4.0ml of normal saline via oral route respectively. The study shows that Dennettia tripetala extract, given at moderate and high doses has no effect on the liver marker enzymes.


CHAPTER ONE

1.0 Introduction

1.1 Background of the Study

The use of medicinal plants has played a major role in nearly every culture on the earth. Herbal medicine was practiced by ancient people of Africa, Asia, Europe and America as an alternative resort to the prevention and cure of illnesses (Iwu, et al. 1989).

The consumption of a variety of local herbs and vegetable by man is believed to contribute immensely to the improvement of human health in terms ofprevention and/or cure of diseases because plant have long served as useful and rational source of therapeutic agents (Okwu, et al. 2005).

Medicinal plants have formed the basis of health care throughout the world since the earliest days of human and have remained relevant in both in developing and developed nations of the world for the various chemotherapeutic purposes. The use of plant derived natural compounds as part of herbal preparation for alternate source of medication continues to play a major role in chemotherapy especially in the third world countries (Okwu, et al. 1999).

1.2 Objective of the Study

The objective of this project work is to ascertain the effect of methanol leaves extract of Dennettia tripetala.

1.3 Statement of the Problem

Poor financial statue is one of the major constraints encountered in the study which was a great hindrance.

1.4 Justification of the Study

This research work will justify or disapprove whether methanol leaf extract of Dennettia tripetala has any effect on the liver markers Alkaline phosphatase (ALP), Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) of Albino rats.

1.5 Limitation of the Study

This project work is limited to the effect of methanol leaf extract of Mmimi on liver marker enzymes which include: Alkaline phosphatase (ALP), Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) of Albino rats.

…

CHAPTER TWO

LITERATURE REVIEW

2.1 Introduction

This chapter focuses on the review of related literature. A literature review includes the current knowledge as well as theoretical and methodological contributions to a particular topic. It documents the state of the art with respect to the topic you are writing. It surveys the literature in the topic selected. In this research work the literature review includes the conceputal review, theoretical framework, the review of related literature …

How to Download the Complete PDF Material (Table of Contents, Abstract, Chapter 1-5, and References)

Above is a preview excerpt of the full study on “The Effects of Methanol Extract of Dennettia Tripetala (Mmimi) on the Liver Marker Enzymes (AST, ALT and ALP) of Albino Rats”. The complete material, including all five chapters, is available for download upon request. Get in touch with us here!

Download Material (Docx)